Bronchodilator responsiveness and atopy in 5-10-yr-old coughers

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Bronchodilator responsiveness and atopy in 5-10-yr-old coughers.

Cough-variant asthma is considered by some to be an asthma phenotype. Bronchodilator responsiveness (BDR) is an undisputed feature of asthma. Of school-aged wheezers, 90% are atopic. Are school-aged coughers who demonstrate BDR also atopic? If so, then it would be reasonable to reserve the diagnosis cough-variant asthma for this particular group. Airway resistance was measured by the interrupte...

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Atopy, airway responsiveness, and genes.

Asthma is a manifestation of bronchial hyperreactivity (BHR) and forms part of the spectrum of atopic disease. Some pedigree studies of atopy have suggested linkage with the high-affinity IgE receptor (FcE RI1) gene on chromosome 11q13, but others find no linkage. The molecular genetics of asthma and BHR have not been studied in the general population. We examined the genetic linkage of the Fce...

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Bronchodilator responsiveness: interpret with caution.

Bronchodilator responsiveness (BDR) is widely considered to be a key diagnostic criterion for asthma, and is used to differentiate asthma from chronic obstructive pulmonary disease (COPD). Currently, the threshold of a 12% increase in FEV1 from baseline following inhaled salbutamol, with at least a 200 ml increase in absolute terms, is recommended as a response indicative of asthma, although re...

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Bronchodilator responsiveness in patients with COPD.

The degree of acute improvement in spirometric indices after bronchodilator inhalation varies among chronic obstructive pulmonary disease (COPD) patients, and depends upon the type and dose of bronchodilator and the timing of administration. Acute bronchodilator responsiveness at baseline was examined in a large cohort of patients with moderate-to-very-severe COPD participating in the Understan...

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Relationship between Pulmonary Function and Exertional Chest Pain in 5-10 Year-old Children

  Background and purpose: Pulmonary problem is one of the non-cardiac causes of exertional chest pain in children. The aim of this study was to evaluate and compare pulmonary function in children with exertional chest pain during rest. Materials and methods: This descriptive analytical cross sectional study was conducted in 200 children aged 10-15 years old in Arak, Iran 2018. The case group (...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2001

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.01.00071901